CURE ACNE CREAM IS AN ANTI ACNE
Acne is one of the most common skin problems in people across the world. Acne leads to severe skin irritation and infection if not treated properly. Acne leaves black spots on the face and neck; it may lead to more infected skin too.
Acne is a group of skin rashes that have different causes.
1-Acne vulgaris - most commonly experienced around puberty, typically of the face and shoulders/chest
2-Acne rosacea - a red rash predominantly on the face
3-Acne keloidalis nuchae (Pseudofolliculitis nuchae) - a rash caused by shaving
4-Acne conglobata (Hidradenitis suppurativa) - chronic abscesses or boils of sweat glands and hair follicles; in the underarms, groin and buttocks, and under the breasts in women
5-Acne cosmetica - acne caused by cosmetics
6-Acne fulminans - an extreme form of acne conglobata
7-Acne medicamentosa - acne caused by starting or stopping a medicine
8-Baby acne - a rash seen on the cheeks, chin, and forehead of infants
9-Chloracne - an acne rash caused by exposure to chlorinated hydrocarbons such as dioxins or PCBs
Acne vulgaris
Acne vulgaris is an inflammatory disease of the skin, caused by changes in the pilosebaceous units (skin structures consisting of a hair follicle and its associated sebaceous gland).
Acne lesions are commonly referred to as pimples, spots or zits.
The condition is most common in puberty.
It is considered an abnormal response to normal levels of the male hormone testosterone.
The response for most people diminishes over time and acne thus tends to disappear, or at least decrease, after one reaches his or her early twenties.
There is, however, no way to predict how long it will take for it to disappear entirely, and some individuals will continue to suffer from acne decades later, into their thirties and forties and even beyond.
Acne affects a large percentage of humans at some stage in life.
The term acne comes from a corruption of the Greek (acme in the sense of a skin eruption) in the writings of Aëtius Amidenus.
The vernacular term bacne or backne is often used to indicate acne found specifically on one's back.
Acne rosacea
Rosacea is a common but often misunderstood condition that is estimated to affect over 45 million people worldwide.
It affects fair-skinned people of mostly north-western European descent, and has been nicknamed the 'curse of the Celts' by some in Ireland.
It begins as erythema (flushing and redness) on the central face and across the cheeks, nose, or forehead but can also less commonly affect the neck and chest.
As rosacea progresses, other symptoms can develop such as semi-permanent erythema, telangiectasia (dilation of superficial blood vessels on the face), red domed papules (small bumps) and pustules, red gritty eyes, burning and stinging sensations, and in some advanced cases, a red lobulated nose (rhinophyma).
The disorder can be confused and co-exist with acne vulgaris and/or seborrheic dermatitis.
Rosacea affects both sexes, but is almost three times more common in women, and has a peak age of onset between 30 and 60.
The presence of rash on the scalp or ears suggests a different or co-existing diagnosis, as rosacea is primarily a facial diagnosis.
The precise pathogenesis of rosacea still remains unknown, but most experts believe that rosacea is a disorder where the blood vessels become damaged when repeatedly dilated by stimuli.
The damage causes the vessels to dilate too easily and stay dilated for longer periods of time or remain permanently dilated, resulting in flushing and redness.
Immune cells and inflammatory mediators can leak from the microvascular bed causing inflammatory pustules and papules, especially with those with papulopustular rosacea.
Acne keloidalis nuchae (Pseudofolliculitis nuchae)
Acne keloidalis nuchae (PFB) is most common on the male face, but it can also happen on other parts of the body where hair is shaved or plucked, especially areas where hair is curly and the skin is sensitive, such as genital shaving (more properly termed psuedofolliculitis pubis or PFP).
After a hair has been shaved, it begins to grow back.
Curly hair tends to curl into the skin instead of straight out the follicle.
PFB can make the skin look itchy and red, and in some cases, it can even look like pimples.
These inflamed papules or pustules can form especially if the area becomes infected.
This is especially problematic for men of African descent and other people with curly hair.
If left untreated over time, this can cause keloid scarring in the beard area.
Acne conglobata (Hidradenitis suppurativa)
Hidradenitis suppurativa or HS is a skin disease that affects areas bearing apocrine sweat glands and hair follicles; such as the underarms, groin and buttocks, and under the breasts in women.
The disease manifests as clusters of chronic abscesses or boils, sometimes as large as baseballs, that are extremely painful to the touch and may persist for years with occasional to frequent periods of inflammation, culminating in drainage of pus, often leaving open wounds that will not heal.
Drainage provides some relief from severe, often debilitating, pressure pain.
Flare-ups may be triggered by stress, hormonal changes (such as monthly cycles in women), humid heat, and clothing friction.
Persistent lesions may lead to scarring and the formation of sinus tracts, or tunnels connecting the abscesses under the skin.
At this stage, complete healing is usually not possible, and progression varies from person to person, with some experiencing remission anywhere from months to years at a time, others may worsen and require surgery in order to live comfortably.
Occurrences of bacterial infections and cellulitis (deep tissue inflammation) may occur at these sites.
HS pain can be difficult to manage.
HS often goes undiagnosed for years because patients are too ashamed to speak with anyone.
When they do see a doctor, the disease is frequently misdiagnosed or prescribed treatments are ineffective, temporary and sometimes even harmful.
There is no known cure nor any consistently effective treatment.
Carbon dioxide laser surgery is currently considered the last resort for those who have advanced to its highest stage, where the affected areas are excised, and the skin is grafted.
Surgery doesn't always alleviate the condition, however, and can be very expensive.
It is possible that there is genetic predisposition to the disease.
(Gao, et al., 2006) HS is not contagious, and isn't affected nor caused by good or bad hygiene. HS is often called an 'orphan illness', due to little research being conducted on the disease at this time.
Because HS is considered a rare disease, its incidence rate is not well known, but has been estimated as being between 1:24 (4.1%) and 1:600 (0.2%).
Hidradenitis suppurativa has been referred to by multiple names in the literature, as well as in various cultures.
Some of these are also used to describe different diseases, or specific instances of this disease.
a-Acne conglobata - not really a synonym - this is a similar process but in classic acne areas of chest and back
b-Acne Inversa (AI) - a new term (Plewig and others) struggling for acceptance
c-Apocrine Acne - a misnomer, out-dated, based on the disproven concept that apocrine glands are primarily involved
d-Apocrinitis - another misnomer, out-dated, based on the disproven concept that apocrine glands are primarily involved
e-Fox-den disease - a catchy term not used in medical literature, based on the deep fox den / burrow - like sinuses
f-Hidradenitis Supportiva - a misspelling
g-Pyodermia sinifica fistulans - an older term, considered archaic now, misspelled here
h-Velpeau's disease - commemorating the French surgeon who first described the disease in 1833
i-Verneuil's disease - recognizing the French surgeon whose name is most often associated with the disorder as a result of his 1854-1865 studies
Causes of Acne conglobata
As this disease is poorly studied, the causes are controversial and experts disagree. However, potential indicators include:
* post-pubescent
* females are more likely than males
* genetic predisposition
* plugged apocrine (sweat) gland or hair follicle
* excessive sweating
* bacterial infection
* sometimes linked with other auto-immune conditions
* androgen dysfunction
* genetic disorders that alter cell structure
Acne cosmetica
Acne cosmetica is a term refering to acne caused by or made worse by cosmetics.
The mechanism was presumably a chemically induced plugging of the pilosebaceous orifice.
This was a significant problem for dermatologists in the 1970s and 1980s, but with the improved formulations produced by cosmetic chemists over the past thirty years, this is now a relatively rare diagnosis in daily practice.
The terms "non-comedogenic" and "non-acne(i)genic" appeared on moisturizers and other cosmetic compounds as re-formulations were introduced, sometimes associated with claims that the products were oil-free or water-based.
Although early work produced lists of comedogenic chemicals in various strengths and vehicles, it became apparent that the actual comedogenicity of a product could not be predicted from its contents; rather the finished product itself needed to be use-tested.
The production of a low-grade folliculitis by some components of the cosmetic product has led to misdiagnosis on occasion.
Acne fulminans
Acne fulminans, also known as Acne Maligna, is a rare severe form of acne.
Acne fulminans is an uncommon severe form of acne.
Acne Fulminans is thought to be a immunologically induced disease.
High concentrations of testosterone and anabolic steroids can cause a rise in sebum and in the population density of the bacteria P acnes.
The increase in the quantity of P acnes or related antigens trigger the immunologic reaction in individuals which leads to Acne Fulminans.
Symptoms include severe lesions, fever, arthritis and failure to respond to antibacterial therapy.
It is best treated with steroids.
On record are 3 sets of identical twins that have all contracted the condition.
A genetic link is considered likely.
Acne fulminans is very rare and tends to be found in acne prone males.
Acne medicamentosa
Acne medicamentosa is acne that is caused or aggravated by medication.
Because acne is generally a disorder of the pilosebaceous units caused by hormones, the medications that trigger acne medicamentosa most frequently are hormones.
Although the male's hormone testosterone is most often blamed, and although men with acne secondary to bodybuilding hormones is seen from time to time, the major hormonal medication that causes acne is the progestin / progestagen present in birth control pills.
Other medications can produce 'acneiform' eruptions (usually pimply bumps and pustules that look like acne).
Some conditions mimic acne medicamentosa.
The most common mimic is the yeast folliculitis produced by an overgrowth of the Malassezia species, often secondary to oral or systemic corticosteroids, or secondary to broad-spectrum antibiotics such as the tetracycline family used in acne.
This is often misinterpreted as 'tetracycline-resistant acne'.
Baby acne
Baby acne, also known as acne neonatorum, is a condition that affects roughly 20% of newborn babies.
Lesions appear at around 2 weeks postpartum and commonly disappear after 3 months.
Lesions include small, red, papules, which mainly affect the cheeks, as well as the nasal bridge of infants.
Infants usually develop neonatal acne because of stimulation of the baby's sebaceous glands by lingering maternal hormones after delivery.
These hormones cross the placenta into the baby and after delivery they cause the oil glands on the skin to form bumps that look like pimples.
Baby acne usually clears up within a few weeks, but it can linger for months.
Tiny bumps on a baby's face after birth that disappear within a few weeks are called milia and are unrelated to baby acne.
Baby acne has recently been described to be caused by saprophytic yeast of the Malassezia species, which cause a primary skin infection leading to the appearance of acne-like pustules.
Initially it was believed to be the common yeast species, Malassezia furfur, which also causes 'cradle-cap' in infants.
However, new publications have pointed to another species, Malassezia sympolais.
Treatment options are still the same for both species, which includes low dose topical antifungals.
Chloracne
Chloracne is an acne-like eruption of blackheads, cysts, and pustules associated with over-exposure to certain halogenic aromatic hydrocarbons, such as chlorinated dioxins and dibenzofurans.
The lesions are most frequently found on the cheeks, behind the ears, in the armpits and groin region.
The condition was first described in German industrial workers in 1897 by Von Bettman, and was initially believed to be caused by exposure to toxic chlorine (hence the name "chloracne").
It was only in the mid-1950s that chloracne was associated with aromatic hydrocarbons.
The substances that may cause chloracne are now collectively known as "chloracnegens".
Chloracne is particularly linked to toxic exposure to dioxins (byproducts of many chemical processes, including the manufacture of herbicides such as Agent Orange) — so much so that it is considered a clinical sign of dioxin exposure.
The severity and onset of chloracne may follow a typical asymptotic dose response curve.
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